International Journal of Medical Anesthesiology
2019, Vol. 2, Issue 2, Part B
Effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain
Author(s): Dr. Ali Fawzi Khiraldeen, Dr. Azhar Kadim Wannas Al Shimary and Dr. Qateralnada Adnan Abbood
Background: Pain is defined as "unpleasant sensory and sensory experience'', associated with actual or potential tissue damage or described in terms of such damage
Objective: To assess the effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain.
Patients and Method: An experimental design was made of a controlled clinical trial type, in patients scheduled for lower abdomen surgery or lower extremities. A sample of 60 patients was studied during the period from October 1 to December 15, 2018, who agreed to participate in the study through of signing consent under information.
Results: It was observed that the time of the rescue analgesia was prolonged in more than 120 min in the case of dexmedetomidine when compared with bupivacaine (p<0.0001); also VAS scores at the time of analgesia rescue for the group with dexmedetomidine were 3.71 ± 1.27 and in the bupivacaine group of 5.7 ± 1.59, the difference of two points of the VAS (p = <0.001) was significant, which demonstrates that dexmedetomidine is effective for prolong postoperative analgesia and decrease the analgesia requirements
Conclusions: Dexmedetomidine at a dose of 5 μg associated with bupivacaine administered intrathecally is more Effective in postoperative analgesia compared with this substance alone in abdominal surgery inferior and lower extremities.
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How to cite this article:
Dr. Ali Fawzi Khiraldeen, Dr. Azhar Kadim Wannas Al Shimary, Dr. Qateralnada Adnan Abbood. Effect of bupivacaine versus bupivacaine plus intrathecal dexmedetomidine in postoperative pain. Int J Med Anesthesiology 2019;2(2):69-71. DOI: 10.33545/26643766.2019.v2.i2b.29