2020, Vol. 3, Issue 3, Part B
A study on efficacy of isobaric Levobupivacaine and Fentanyl with Isobaric Ropivacaine and Fentanyl in patients undergoing TURP at a tertiary care hospital
Author(s): Dr. Ranjini Basavaraj Nataraj, Dr. Shankaranarayana P and Dr. Ganapati P
Abstract: For decades, lignocaine had been the local anaesthetic of choice for spinal anaesthesia. Its advantages are rapid onset of action and good motor block manifested as good muscle relaxation. Its use was limited by its short duration of action and has been implicated in transient neurologic symptoms and cauda equina syndrome following intrathecal injection. Bupivacaine is three to four times more potent than lignocaine and has longer duration of action. The study includes 30 males in each group (group R and group L) satisfying the inclusion criteria. Group R: 2.6 cc of 0.75% isobaric ropivacaine (19.5mg) with 0.4cc of fentanyl (20 microgram).Group L: 2.6 cc of 0.5% isobaric levobupivacaine (13 mg) with 0.4cc of fentanyl (20 microgram). This study reveals that the intrathecal 2.6ml of 0.75% isobaric ropivacaine with fentanyl 20μg provides adequate anaesthesia for TURP cases. Ropivacaine achieves a longer duration of sensory and motor blockade as compared with 0.5% isobaric levobupivacaine. With the quality and duration of block achieved with ropivacaine, it can be justified to use it for TURP cases. In conclusion, 0.75% isobaric ropivacaine with fentanyl prolongs sensory and motor block durations providing adequate anaesthesia for patients undergoing TURP under SAB and post operative analgesia compared to 0.5% levobupivacaine without causing any difference in significant side-effects. Hence, ropivacaine with fentanyl in spinal anaesthesia for TURP cases is a better alternative compared to levobupivacaine with fentanyl.
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How to cite this article:
Dr. Ranjini Basavaraj Nataraj, Dr. Shankaranarayana P, Dr. Ganapati P. A study on efficacy of isobaric Levobupivacaine and Fentanyl with Isobaric Ropivacaine and Fentanyl in patients undergoing TURP at a tertiary care hospital. Int J Med Anesthesiology 2020;3(3):68-73. DOI: 10.33545/26643766.2020.v3.i3b.150