International Journal of Medical Anesthesiology
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P-ISSN: 2664-3766
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International Journal of Medical Anesthesiology

2021, Vol. 4, Issue 2, Part B
Assessment of intraperitoneal instillation of levobupivacaine plus Dexmedetomidine versus ropivacaine plus Dexmedetomidine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy: A comparative study


Author(s): Dr. Suresh Janapati, Dr. T Anusha and Dr. Manda Hiresh Nagrale

Abstract: Background: The present study was undertaken for assessing and comparing the efficacy of Intraperitoneal Instillation of Levobupivacaine plus Dexmedetomidine and Ropivacaine plus Dexmedetomidine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy.
Materials & methods: 40 patients were randomly divided into two groups of 20 each using sealed envelopes. Group A: Patients were given levobupivacaine plus Dexmedetomidine, and Group B: patients were given ropivacaine plus dexmedetomidine. Proforma was made and complete demographic and clinical profile of all the patients was recorded. Postoperatively the patients were assessed for pain utilizing visual analogue scale (VAS). Mean time to first analgesic requirement was recorded. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software.
Results: In the present study, mean age of the subjects of Group A and group B was 42.8 years and 45.3 years respectively. There were 12 males and 8 females in group A and 11 males and 9 females in group B. Mean VAS score among the subjects of group A at baseline, 1 hour, 6 hours and 12 hours was 1.3, 2.3, 2.5 and 1.9 respectively. Mean VAS score among the subjects of group B at baseline, 1 hour, 6 hours and 12 hours was 1.4, 2.7, 3.1 and 1.8 respectively. While comparing the VAS at different time intervals, non-significant results were obtained. Mean time to first analgesic requirement among the patients of group A and group B was 315.8 minutes and 267.4 minutes respectively. Significant results were obtained while comparing the mean time to first analgesic requirement among the subjects of the two study groups.
Conclusion: Analgesia provided by Levobupivacaine plus Dexmedetomidine is significantly better than Ropivacaine plus Dexmedetomidine in terms of first analgesic requirement.


DOI: 10.33545/26643766.2021.v4.i2b.235

Pages: 88-90 | Views: 40 | Downloads: 29

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How to cite this article:
Dr. Suresh Janapati, Dr. T Anusha, Dr. Manda Hiresh Nagrale. Assessment of intraperitoneal instillation of levobupivacaine plus Dexmedetomidine versus ropivacaine plus Dexmedetomidine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy: A comparative study. Int J Med Anesthesiology 2021;4(2):88-90. DOI: 10.33545/26643766.2021.v4.i2b.235
International Journal of Medical Anesthesiology