International Journal of Medical Anesthesiology
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P-ISSN: 2664-3766
E-ISSN: 2664-3774
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International Journal of Medical Anesthesiology

2021, Vol. 4, Issue 2, Part C
Attenuation of pressor response to laryngoscopy and intubation with topical lignocaine 10% spray in the controlled hypertensive patients


Author(s): Rajdeep Kour, Neha Sharma and Maninder Singh

Abstract: Laryngoscopy and tracheal intubation is invariably associated with a reflex sympathetic pressor response resulting in elevated heart rate and blood pressure. There are many studies conducted to attenuate this pressor response, the present study is undertaken to compare efficacy of 10% lignocaine spray with normal saline spray applied before induction in attenuating the pressor response to laryngoscopy and intubation in controlled hypertensive patients.
Methods: 60 patients of either sex aged between35-60 years, belonging to ASA I and II undergoing elective surgery requiring general anaesthesia with endotracheal intubation were included. Patients were randomly divided in two groups of 30 patients each. Group I (Study group) received topical lignocaine 10% spray 2 minutes before intravenous induction. Group II (Control group) received topical normal saline 2 minutes before intravenous induction.
Results: Showed that the topical lignocaine 10% spray significantly attenuates the rise in mean systolic blood pressure, diastolic blood pressure and heart rate when compared with the baseline as well as the control group. There was a statistically significant (p<0.05) increase in heart rate, systolic and diastolic blood pressure in group II when compared to group I and baseline values.
Conclusion: Study concluded that topical lignocaine 10% spray did not completely abolish the rise in heart rate, SBP and DBP but only attenuate it when compared with the baseline or control group.


DOI: 10.33545/26643766.2021.v4.i2c.253

Pages: 189-192 | Views: 181 | Downloads: 86

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How to cite this article:
Rajdeep Kour, Neha Sharma, Maninder Singh. Attenuation of pressor response to laryngoscopy and intubation with topical lignocaine 10% spray in the controlled hypertensive patients. Int J Med Anesthesiology 2021;4(2):189-192. DOI: 10.33545/26643766.2021.v4.i2c.253
International Journal of Medical Anesthesiology