2020, Vol. 3, Issue 4, Part A
to study the effect of intravenous dexmedetomidine and clonidine for attenuating hemodynamic response with proseal LMA in pneumoperitoneum
Author(s): Dr. Manoj Sham Adhav and Dr. Amit Kumar
Abstract: Background: 75 individuals in the age group between 18-50 years belonging to ASA class I and II undergoing laparoscopic upper and lower abdominal surgeries were selected. A detailed history, complete physical examination and baseline investigations were done for all patients.
Method: Data was collected in pretested proforma meeting the objectives of study. Preoperative assessment was done for each patient and written informed consent was taken. Proper nil per oral status was checked before proceeding for each case. No hypnotic medication was given on the evening before surgery. Patients were pre medicated with injection glycopyrrolate 0.2milligrams in the preoperative room.
Result: In the dexmedetomidine group, the mean pulse rate reduced at 0 min in comparison and continued its fall it 45 minutes, then showed a slight rise till end of the 180 minutes. In the clonidine group, the mean pulse rate keep on increasing till 25 minutes in comparison to the preoperative value, then slight reduction at 35 minutes, then increased at 45 min, then reduced at 60 min, then increased till 180 minutes.
Conclusion: In our present study we found easy insertion of proseal laryngeal mask airway with no complications. We used dexmedetomidine and clonidine @ 1 mcg/kg body weight to attenuate hemodynamic response to pneumoperitoneum during laparoscopic surgery and we found better control of heart rate, systolic blood pressure, diastolic bloodpressure and mean arterial pressure with dexmedetomidine group than with clonidine group. In our present study we found no change in oxygen saturation and endtidal carbon dioxide.
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How to cite this article:
Dr. Manoj Sham Adhav, Dr. Amit Kumar. to study the effect of intravenous dexmedetomidine and clonidine for attenuating hemodynamic response with proseal LMA in pneumoperitoneum. Int J Med Anesthesiology 2020;3(4):27-30. DOI: 10.33545/26643766.2020.v3.i4a.162