International Journal of Medical Anesthesiology
2020, Vol. 3, Issue 4, Part B
Comparing the efficacy of prophylactic use of hydrocortisone and low dose ketamine for prevention of shivering under spinal anesthesia
Author(s): Karthika Rathina Kumar, UG Thirumaaran and Selvakumaran
Abstract: Introduction: The thermoregulatory system plays an important role in coordinate the defense system against the environment in regulating the normal body temperature in homoeothermic species. Hypothermia result is an important complication-Shivering, which is a complicated response of the body resulting in a pattern of muscular activity.
Aim: This study aims to compare the efficacy of I.v. hydrocortisone with I.v. low dose ketamine for prevention of shivering during spinal anesthesia.
Material & Methods: A Prospective Randomized trial with a sample size of 60 where patients allocated randomly using slot into 2 groups of Group-H (n=30) who received Inj. Hydrocortisone 2mg/kg and Group K (n=30) who received Inj. Ketamine 0.25mg/kg undergoes lower abdominal surgery under spinal anesthesia with 0.5% Bupivacaine of dosage 3ml. Parameters such as heart rate, blood pressure, oxygen saturation, temperature, were observed intraoperatively and postoperatively. The shivering grade, sedation score, patient requiring Inj. Pethidine as a rescue dose, motor, and sensory block was observed along with any side effects such as bradycardia, hypotension, or desaturation.
Result: In this study, there was no statistically significant difference (p>0.05) between the two drug groups in the grades of shivering. Clinically there were lower grades of shivering in the Hydrocortisone group when compared to the ketamine group at all timelines.
Conclusion: I.v. hydrocortisone 2mg/kg compared with the low dose I.v. ketamine 0.25mg/kg was clinically effective in reducing the incidence and intensity of shivering under spinal anesthesia on prophylactic use for lower abdominal surgery.
Pages: 100-106 | Views: 93 | Downloads: 41
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How to cite this article:
Karthika Rathina Kumar, UG Thirumaaran, Selvakumaran. Comparing the efficacy of prophylactic use of hydrocortisone and low dose ketamine for prevention of shivering under spinal anesthesia. Int J Med Anesthesiology 2020;3(4):100-106. DOI: 10.33545/26643766.2020.v3.i4b.172