2021, Vol. 4, Issue 2, Part A
Effect of oral clonidine on perioperative haemodynamic response and post-operative requirement of analgesic for patients undergoing laparoscopic surgery
Author(s): Dr. Dimple K Pandya, Dr. Tirth S Patel, Dr. Krupal Patel, Dr. Manisha Sharma and Dr. Karan A Batavia
Abstract: Laparoscopic surgeries provide direct visualization with small incisions. It reduces postoperative pain and discomfort to patients. It helps in early post-operative recovery and reduces morbidity and mortality. It also reduces the requirement of post-operative analgesics and results in early mobilization. Laparoscopic surgeries generally require creation of pneumoperitoneum which is insufflation of the peritoneal cavity with some gas, usually Carbon Dioxide. Increase in intra-abdominal pressure due to pneumoperitoneum along with position required for better access during surgeries causes several pathophysiological changes in the body. These changes make anesthetic management more challenging as compared to other surgeries.
Since the hemodynamic stress response are inevitable with insufflation of CO2  In Laparoscopic surgeries, various methods like adequate administration of crystalloids (preloading), different pharmacological agents like opioids, direct vasodilators like nitroglycerine, α2-agonists, inhalational anesthetics are used.
In our study, we determined to observe and compare the effects of oral preparation of clonidine on patients undergoing elective laparoscopic surgeries. We observed the effect of clonidine as premedication for attenuation of hemodynamic changes perioperatively, and postoperative sedation, analgesia.
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How to cite this article:
Dr. Dimple K Pandya, Dr. Tirth S Patel, Dr. Krupal Patel, Dr. Manisha Sharma, Dr. Karan A Batavia. Effect of oral clonidine on perioperative haemodynamic response and post-operative requirement of analgesic for patients undergoing laparoscopic surgery. Int J Med Anesthesiology 2021;4(2):19-22. DOI: 10.33545/26643766.2021.v4.i2a.228