International Journal of Medical Anesthesiology
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P-ISSN: 2664-3766
E-ISSN: 2664-3774
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International Journal of Medical Anesthesiology

2021, Vol. 4, Issue 4, Part B
A prospective, randomized and double blinded clinical comparative study to evaluate dexmedetomidine and nitro-glycerine for controlled hypotensive anaesthesia elective spine surgeries


Author(s): Dr. Polapally Venu and Dr. R Gopinath

Abstract: Aim: To compare the efficacy of and safety of dexmeditomidine versus nitroglycerine during hypotensive anaesthesia induced by either drug in adult patients posted for elective spine surgeries.
Material and Methods: This was a prospective, randomized, and double blinded clinical comparative study conducted in the Department of Anaesthesiology, ESIC Medical College, Sanath Nagar, Hyderabad, Telangana, India for the period of 1 year. 100 participants belonging to ASA class I or II between 20 and 55 years of age scheduled for elective spine surgeries were include in this study. The study drug dexmeditomidine was given to group DX in the dose of 1 micro gram/kg body weight in a 600 seconds infusion before induction diluted to 10 ml with normal saline followed by maintenance dose at infusion rate of 0.2- 0.7 microgm/kg. The group NG received 10 ml plain normal saline over 600 seconds before induction followed by maintenance dose of nitroglycerine at an infusion rate of 0.5-10 microgm/kg/min. different parameter were compared in both the groups.


DOI: 10.33545/26643766.2021.v4.i4b.323

Pages: 65-70 | Views: 346 | Downloads: 170

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How to cite this article:
Dr. Polapally Venu, Dr. R Gopinath. A prospective, randomized and double blinded clinical comparative study to evaluate dexmedetomidine and nitro-glycerine for controlled hypotensive anaesthesia elective spine surgeries. Int J Med Anesthesiology 2021;4(4):65-70. DOI: 10.33545/26643766.2021.v4.i4b.323
International Journal of Medical Anesthesiology