2023, Vol. 6, Issue 4, Part A

One hundred five patients were included, their ages ranging from (25 to 80) years old suffering from chronic knee joint pain for more than 3 months due to mild, moderate, and advanced osteoarthritis. The cases were documented by detailed history-taking, clinical examination, x-ray findings, lab investigations, and ultrasound evaluation. The procedure comprised intra articular ozone (O₃) therapy, ozone with steroid, or ozon with hyaluronic acid injection, for 105 patient. Aspiration of the effusion of an amount ranging from (15-75 ml) form 24 patients, volume and concentration of medical ozone was used(15-20 ml of 20-30 μg/ml), divided into five sessions by one week interval regularly using a lateral or medial suprapatellar approach under ultrasound guidance by a short axis view over the suprapatellar recess. The aim of this study is to assess the (Role of Ozone and Its potentiation effect on Steroids and Vesicosupplement) Injections in knee OA. The current study revealed that good responses regarding pain and joint function were commonly obtained in mild (85.7%) and moderate (81.5%) OA, followed by advanced OA (51.4%), respectively, in comparison to moderate or poor responses obtained in mild OA (14.3%), moderate OA (18.5%), and advanced OA (48.6%), respectively. Ozone is a promising interventional pain treatment for patients with knee OA if it is used in the form of weekly sessions and continuously for 5 sessions, regardless of the joint, and it is advisable to use O₃ routinely at the end of interventional pain procedures safely because of its properties.