2024, Vol. 7, Issue 1, Part A
Prilocaine compared with bupivacaine in spinal anesthesia for lower abdominal day case surgeries: A prospective randomized double-blind controlled study
Author(s): Amr Ahmed Arfa, Ghada Fouad Elbradey, Sameh Mohamed Fathy Sadek and Wail Ebrahim Messbah
Abstract: Background: Day-case spinal anaesthesia using hyperbaric prilocaine, a short-acting local anesthesia, has a short duration of action and a low incidence of transient neurological symptoms (TNS). Purpose: The current study aim to evaluate and compare hyperbaric prilocaine 2% and hyperbaric bupivacaine 0.5% for spinal anesthesia in lower abdominal day case surgeries. Methods: This work was conducted as a prospective randomized controlled double-blind study on a total of 70 individuals, both male and female, who were planned for day case surgeries using spinal anaesthesia. The participants were allocated into two groups: group I, who received a dose of 15 mg HB 0.5%, and group II, who received a dose of 60mg HP 2% Results: The group that received prilocaine had a rapid onset of sensory (3.9± 0.36 min) and motor block (6 ± 0.7 min) compared to the other group (p<0.001). The Prilocaine group exhibits a shorter duration of sensory (92.4 ± 2.5 min) and motor blockage (113.7 ± 8.8 min) compared to the bupivacaine group (193.6 ± 10.9) min for sensory blockage and (261.9 ± 19.8) min for motor block). The Prilocaine group demonstrated a significantly less time to walk without assistance (120.7±7.8 min) and void spontaneously (256.4±21.5 min) compared to the corresponding times in group I, where the duration to walk without assistance and void spontaneously were (301.8±13.9 min) and (345.4±24.5 min) correspondingly. Conclusion: Group II offers rapid onset, less duration of action, and rapid recovery in ambulatory surgeries contrasted to Group I in lower abdominal day-case surgeries.
DOI: 10.33545/26643766.2024.v7.i1a.442
Pages: 14-19 | Views: 110 | Downloads: 63
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How to cite this article:
Amr Ahmed Arfa, Ghada Fouad Elbradey, Sameh Mohamed Fathy Sadek, Wail Ebrahim Messbah. Prilocaine compared with bupivacaine in spinal anesthesia for lower abdominal day case surgeries: A prospective randomized double-blind controlled study. Int J Med Anesthesiology 2024;7(1):14-19. DOI: 10.33545/26643766.2024.v7.i1a.442
