International Journal of Medical Anesthesiology
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P-ISSN: 2664-3766
E-ISSN: 2664-3774
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2024, Vol. 7, Issue 1, Part A

Efficiency of high-flow nasal cannula (HFNC) compared to conventional oxygen therapy (COT) on preventing reintubation in critically ill patients: A randomized controlled clinical trial


Author(s): Fatma Sabry Shaalan, Hesham Ibrahim Eltatawy, Salah-Eldin Ibrahim ElSherif, Hala Mohey El-Deen El-Gendy, Rehab Said Elkalla

Abstract:
Background: Postoperative respiratory complications rank as the second most common complications after surgery and impose a significant strain on healthcare systems. This research aimed to evaluate the efficacy of preventive immediate application of high-flow nasal cannula (HFNC) in comparison to conventional oxygen therapy (COT) after extubating, with the goal of minimizing the reintubation rate.
Methods: A prospective randomized controlled clinical study was carried out on a cohort of 146 adult patients who had undergone extubation. The participants were allocated into two equal groups using a randomization process: Group A (control group) is the designated group that serves as a standard for comparison in an experiment. There were 73 people diagnosed with COT. Administered by nasal cannula or face mask. Group B is using HFNC therapy. There were 73 patients that were treated with HFNC.
Results: Comparing the Rox between the two studied groups after 6, 12 hrs. Showed a statistically significant increase in group B than group A, while there was not statistically significance difference after 24, 36 hrs. There was a statistically significance difference between the two groups when we compared the P/F ratio at 1, 4, 12, 24, and 36 hours. The HLS range for Group A (COT) was (3.0 - 12.0) compared to Group B (HFNC) (3.0 - 10.0) (P<0.001). This difference was statistically significance.
Conclusions: Post-surgical patient at high risk of ALI, the use of immediate HFNC compared to COT reduce the reintubation rate.


DOI: 10.33545/26643766.2024.v7.i1a.449

Pages: 58-66 | Views: 318 | Downloads: 160

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International Journal of Medical Anesthesiology
How to cite this article:
Fatma Sabry Shaalan, Hesham Ibrahim Eltatawy, Salah-Eldin Ibrahim ElSherif, Hala Mohey El-Deen El-Gendy, Rehab Said Elkalla. Efficiency of high-flow nasal cannula (HFNC) compared to conventional oxygen therapy (COT) on preventing reintubation in critically ill patients: A randomized controlled clinical trial. Int J Med Anesthesiology 2024;7(1):58-66. DOI: 10.33545/26643766.2024.v7.i1a.449
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