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International Journal of Medical Anesthesiology
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P-ISSN: 2664-3766
E-ISSN: 2664-3774
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2025, Vol. 8, Issue 4, Part A

Naloxone responsive delayed emergence following low dose fentanyl administration under general Anesthesia


Author(s): Anupreet Kaur and Vibha Mahajan

Abstract: Perioperative analgesia frequently employs opioids; nonetheless, unforeseen opioid reactions may arise in patients lacking a previously recorded opioid allergy. We present the case of a 60-year-old female with multiple documented drug allergies to Ibuprofen, Asprin, Quinine, Placenta Extracts, and Ampicillin, who underwent laparoscopic cholecystectomy under general anaesthesia. The intraoperative course was unremarkable; however, the patient demonstrated delayed emergence from anesthesia, marked by unresponsiveness and pinpoint pupils. Suspecting opioid-induced central nervous system depression, injection Naloxone was administered leading to a rapid enhancement in the patient's consciousness and respiratory function. This case underscores the essential necessity of diligent reversal from anesthesia surveillance, prompt identification of opioid-related complications, and swift therapeutic action. Prompt clinical assessment and decisive intervention were crucial in averting potentially life-threatening respiratory depression.

DOI: 10.33545/26643766.2025.v8.i4a.599

Pages: 25-27 | Views: 129 | Downloads: 75

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International Journal of Medical Anesthesiology
How to cite this article:
Anupreet Kaur, Vibha Mahajan. Naloxone responsive delayed emergence following low dose fentanyl administration under general Anesthesia. Int J Med Anesthesiology 2025;8(4):25-27. DOI: 10.33545/26643766.2025.v8.i4a.599
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